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211 Uppsatser om T cells - Sida 1 av 15

Solceller för flerbostadshus : En teknisk rapport för HFAB

This examination paper is about the potential for Solar cells on apartment blocks. The technology with using solar cells for manufacturing electricity, has been on the market for a while, but recently the new installations of solar cells has increased. Solar cells are suited for placements on buildings but are expensive to obtain. The municipal real-estate company is interested in solar cells but wants to know more before they invest in the technology. This report contains an account of the solar cell and a guide to how a connection to the grid is accomplished.

Breast cancer stem cells : evidence and contradictory views

This literature study aims to examine the existence of cancer stem cells in breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. These tumour initiating cells have shown to possess many characteristics similar to those of adult stem cells, which is why they are often referred to as cancer stem cells. Both cell types have the capacity of asymmetric division and have shown to possess mechanisms of resistance to both apoptosis and cancer drugs. The cancer stem cell theory elucidates many biological aspects such as the heterogeneity of tumours and the relapse of many cancers after what appeared to be successful treatments.

Optimization of Lentivirus Production for Cancer Therapy

Vectors based on lentivirus backbones have revolutionized our ability to transfer genesinto many cell types. Lentiviral vectors integrate into the chromatin of targeT cells and do not transfer any viral genes causing vector replication. Both of these features arecommonly used in gene therapy and have been used clinically in individuals sufferingfrom cancer, infections and genetic diseases. It has been discovered that T-cells can be genetically modified to be used as effective weapons against cancer: therefore virus mustbe produced to deliver the gene of interest into the T-cells. In this project, lentiviralvectors have been produced to transfer the gene coding for a chimeric antigen receptor(CAR) which is directed to CD19 on B-cells.

Solenergi i Norrra Djurgårdsstaden

This report will examine various solar energy technologies in order to decide if they could be applied in the Royal Seaport. The Royal Seaport is a Swedish urban district under development in Stockholm, with the goal of becoming a sustainable district. Two main techniques, solar collectors and solar cells, including sub-categories, are addressed in this report. Another sub-category, a hybrid system, will also be mentioned. The main difference between solar collectors and solar cells is the type of energy produced by the system.

Generation of mutated expression plasmid KRT1 and comparison of HaCaT cells transfected with expression plasmid KRT1 or KRT10 concerning keratin aggregates

Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. Since medicines are hard to investigate and produce mainly due to lack of reproducible model systems, there is no good treatment available for this disease today. In this article we describe how an in vitro model consisting of cells from a stable cell line transfected with expression plasmids to mimic patienT cells, may be a possible alternative for screening compounds for therapies. The first step was to generate an expression plasmid required to complete the in vitro model.

4-1BB is up-regulated in human mast cells, when exposed to tumor conditioned medium

MasT cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al., 2010). In an expression array study (Wensman et al, submitted manuscript) performed on mouse masT cells exposed to tumor conditioned medium, the gene 4-1BB was among the most up-regulated genes compared to control medium. 4-1BB codes for a membrane receptor protein of the tumor necrosis factor superfamily and has been shown to be important in T cell regulation in tumor diseases. This study was performed to investigate if human masT cells up-regulate 4-1BB when they get exposed to tumor conditioned medium.

Solceller som energikälla och solskydd för tält

This degree project is an investigation of solar cells and their ability to deliver electric power as well as reducing the need for cooling. The main object of interest is a BASE-X shelter. The shelter is purchased by the Swedish Defence Materiel Administration, FMV to be used for command and camp in the new force called Nordic Battlegroup, NBG. The demand on the equipment is firstly that it should have a small weight to be easy to transport and handle and secondly to be easy to bring up fast. Therefore the choice of solar cell technology fell on thin film cells.

Industrialiserat byggande

The industrialization of construction is increasing in Sweden which leads to higher demands of prefabricated components and cells. But what does the business of construction think of the industrialized business and what can be done in order to decrease faults and errors with these products? Today we have many manufacturers who have different technical solutions which might lead to difficulties when assembling components and cells at the building site. But by trying to make a more opened market, with possibly standardized connections details and improving the communication between the different participants, the prefabricated components and cells can be made and assembled with less errors. This is something that needs to be done in order to establish a more secure business, and especially when working with new companies and methods, when using industrialized products..

SOLPANELERS MÖJLIGHETER, EN AKTUELL RAPPORT FÖR MONTAGE PÅ FASTIGHETEN KORNHILL

This thesis deals with the possibilities of installing solar panels on a property, the building is owned by Kornhillschurch and called Kornhill. The owners of the property wanted to learn more about potentials for installation of solar panels on the property, therefore we described different types of solar cells and solar cells essential function to generate electricity in the report. Different factors that are limiting the generated energy are mentioned.An investigation of the property?s potential has been made in order to consider different designs. When sites that were considered suitable for solar cells were selected, different design options were made, one for each site.

Evaluation of a method for determinationof glutathionereductase activity inerythrocytes

Glutathione (GSH) is a molecule that consists of three amino acids: glutamic acid, cysteine and glycine. GSH has several important functions: to protecT cells from free radicals, reactive oxygen species and oxidative stress. GSH exists in a reduced form, GSH, and in an oxidized dimeric form, glutationdisulfid, GSSG. The enzymes glutathionereductase (GR) catalyses the reduction of GSSG back to GSH. Nicotinamide adenine dinucleotide phosphate (NADPH) is required as a coenzyme in the reaction.

Småhusutformning och solenergiutnyttjande

This paper goes through solar energy and what uses it has. It is also a guide in the choice of solar collectors forthe real estate that I have drawn for the thesis work.Solar energy is a renewable source of energy from the Sun's light. Energy can be used to produce both heat andelectricity through solar collectors and solar cells. Some of the benefits of solar energy is that it is completely freeto extract, environmentally friendly and virtually maintenance-free. Disadvantages are that the technology isexpensive, does not cover the entire energy needs and takes a long time until it pays.

Energieffektivisering ombord M/S Sydfart : Med hjälp av solceller

The goal of this paper is to find out how solar cells can improve energy efficiency on-board M/S Sydfart. The paper is based on a number of energy measurements on board the M/S Sydfart. The solar surface is calculated by measuring the available space for installing solar panels. Global radiation data is taken from STRÅNG's database, the data is then used to calculate the theoretical power produced by the solar cells. Energy efficiency is analysed in two ways.

Solceller ? Solen är ju gratis! : En undersökning av huruvida solceller är ett fördelaktigt energisystem med avseende på tekniska och ekonomiska aspekter

This report is a result of a bachelor thesis at the school of Architecture and the Built environment (corresponding to 15 HP) and is written during spring 2012 at the Royal Institute of Technology (KTH) in Stockholm. The Bachelor's essay is based on the design and dimensioning of a house which is located at a predetermined site in Malmo, Sweden.The idea is to construct a house that is appropriate to use for an average Swedish family of four family members. The house is designed in a modern way with respect to ease of access and disabled facilities. The installation that have been considered are heating, ventilation, sanitation and electricity. Construction calculations and material selection are also discussed.Furthermore, a study about photovoltaic cells has been done.

The role of cell cycle control mechanisms in regulated and sustained cell proliferation

The cell cycle is the time a cell spends between two cell divisions. The cell cycle includes several parallel processes, all of which must be completed before a cell is mature for dividing. In the first place, all subcomponents (RNA, protein and membrane lipids) need to double in quantity and this occurs continuously through the cell cycle. Furthermore, the genome and some chromosomal proteins must double and this take place during a limited interval in the middle of the cell cycle (S-phase). On either side of the S-phase are two "gaps" which is called G1 and G2. When the cell has passed a point in the G-phase they are irreversibly programmed to progress through the remaining of the cell cycle and will undergo the next cell division. When a cell have passed a point in the G1 phase, approximately four hours after mitosis, a normal cell is in a state of indecision.

Övertoner i elnät vid Skellefteå lasarett : Harmonics in power grids at Skellefteå Hospital

The goal of this paper is to find out how solar cells can improve energy efficiency on-board M/S Sydfart. The paper is based on a number of energy measurements on board the M/S Sydfart. The solar surface is calculated by measuring the available space for installing solar panels. Global radiation data is taken from STRÅNG's database, the data is then used to calculate the theoretical power produced by the solar cells. Energy efficiency is analysed in two ways.

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